Visual signs and symptoms of progressive supranuclear palsy
نویسندگان
چکیده
منابع مشابه
Visual hallucinations in progressive supranuclear palsy.
records were collected on an annual basis and all pertinent information was entered into a database. For patients with cognitive impairment a caregiver with knowledge of the patient’s family and personal medical history completed the registry form. Upon death, remaining medical records were collected and neuropathological analyses were performed. Patients were brought to autopsy according to st...
متن کاملVisual–vestibular interaction in progressive supranuclear palsy
We measured the stability of gaze during horizontal head rotations at 1-3 Hz in four patients with progressive supranuclear palsy (PSP), while they viewed a stationary target. Median gain of compensatory eye movements was 0.94, similar to control subjects. During rotation in darkness, median gain of vestibulo-ocular reflex (VOR) was 0.88, similar to controls. Conversely, the median gain of smoo...
متن کاملFamilial progressive supranuclear palsy.
A progressive extrapyramidal syndrome and dementia occurred in three members of one family. The age of onset was in the seventh decade and the affected individuals showed many of the clinical features of progressive supranuclear palsy (PSP). Necropsy of one individual revealed the neuropathological features of PSP. We propose that this family has a familial form of PSP and review the evidence i...
متن کاملProgressive Supranuclear Palsy (PSP)
Introduction: Progressive supranuclear palsy (PSP) is a rare neurodegenerative disorder producing characteristic eye movement abnormalities in the classic presentation. The disease pathologically is marked by accumulation of abnormal tau proteins. There are useful MRI features, however the diagnosis remains clinical in the majority of cases, and no objective diagnostic test exists. Treatment at...
متن کاملProgressive supranuclear palsy.
This review concentrates on the molecular pathology of the protein tau, including its expression in various regions of the brain. The role of post-translational modifications in fibrillogenesis is also discussed, particularly hyperphosphorylation and glycation. However, the initiating event that causes aberrant tau processing remains unclear.
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ژورنال
عنوان ژورنال: Clinical and Experimental Optometry
سال: 2011
ISSN: 0816-4622,1444-0938
DOI: 10.1111/j.1444-0938.2010.00504.x